BIOL 308Principles of Molecular Biology
- Units
- 0.50
- Faculty
- Science
- Subject
- Biology
When it runs
- F24
- W25
- S25
- F25
- W26
- S26
- F26
- W27
- S27
Ran in 5 of the last 7 terms. Winter 2027: not on the schedule. Spring 2027: schedule not out yet.
Prokaryote and eukaryote genome structure and replication; mechanisms of gene expression and regulation.
Prerequisites
Antirequisites
None listed.
Leads to
Fall 2026 sections
| Section | Class | Enrolled | Meets |
|---|---|---|---|
| LEC 001 | 7125 | 302 / 387 | MWF 10:30–11:20 |
Reviewed on UW Flow
43% liked it18% easy77% useful
From 152 ratings and 46 comments on UW Flow. The most helpful comments, quoted as written, without names. Read them all on UW Flow.
On the first day of lectures Dr. Miskovic told the class that there were study questions, and to do them. The study questions are the only content you need. Do not make notes as you would traditionally for a course, exclusively focus on the content covered in those questions. You also start them immediately after the content was covered in lecture, and review them frequently - as Dr. Miskovic will tell you, they comprise 70% of the questions on examinations. Do NOT leave them until the end, or there's a good chance you'll fail the course. Finally, do the practice final multiple times as well.
Jan 2016 · liked it · 4 found this helpfulOn UW FlowRemove this
if someone put a trigger to my head and asked me just ONE THING I learned in this course, I would probably be dead. I still don't know how I passed. I think I actually got a 70 and I'd say that's a bloody miracle. So I guess what I'm trying to say is that it's not impossible, but I must admit, at a certain point in time I was so doomed I stopped studying for the exam because I figured no amount of studying was going to help me. It's probably not a useless or impossible course but it's just not worth the decline in mental health (for me at least, since I value my mental health).
Nov 2022 · didn’t like it · 3 found this helpfulOn UW FlowRemove this
Im going to try and stay away from making statements like I hate this course and give you useful information.
The course is filled with a MASSIVE amount of information that it is not possible to remember. I recommend going to lectures but keep in mind I would end up sleeping through half of it. The slides are filled with so much information too. It is a pipe dream to expect to remember all of that.
So what to do? Try and go thru the slides, really skim and and pick out core topics and concepts that seem testable and absorb that (you have to use your discretion and common sense, if you were the examiner, what would you test). Really do this exercise, it helps get rid of all the other…May 2023 · didn’t like it · 2 found this helpfulOn UW FlowRemove this
This course was just a nightmare. There is just an overload of information and minute details. But only a few certain ideas and areas are actually tested. I feel like if that is what was expected of us to learn than the prof. should have spent more time on those parts.
The material comes hard and fast, with little time for explanation. This course wasn't one I enjoyed, even though I love Molecular Biology. If you can choose not to take this course, I would not take this course.Dec 2014 · didn’t like it · 2 found this helpfulOn UW FlowRemove this
Great course, I hate how much fundamental filler crap you have to get through before you learn anything really interesting. If you're into molecular biology there some incredible insights into splicing and transcriptional mechanisms i found fascinating. You're evaluated on your ability to finish the study question or your ability to amass a library or them and regurgitate them on the exam. There is a lot of material despite have a clear set of question to focus you brain on the important stuff. Its definitely a course you need a few days to let the material sink in before the exam.
Aug 2014 · liked it · 2 found this helpfulOn UW FlowRemove this
Discussed on r/uwaterloo
181 posts and comments in 147 threads mention BIOL 308, September 2011 to December 2024. Quoted word for word, newest first; each reply sits under the post and the comment that started its branch. Search r/uwaterloo for newer posts.
Fall 2024
People who already graduated but still visit this site—-any profs you remember fondly? 64 points, 65 comments
u/TurboTwinky28: “For anyone in Bio Bruce Wolff - Biol 308 - I felt that Wolff did a great job getting us through the mountain of content. He was clear on what is the core material and what is just nice-to-know or "might help you memorize" details. …”
Fall 2023
Biophysics minor 1 point, 1 comment
u/Big_Steak7381: “… The biology courses needed for this minor are: BIOL 130 (intro cell bio), BIOL 239 (genetics), BIOL 308 (molecular bio). Do let me know what I can do about this and how I would approach this if I would take the risk. …”
u/dumbo-en-waterloo: “I think out off the three courses you described BIOL 308 is the worst one; it’s an insane about if content and you need to know it fairly well in order to do ok in it”
Biol 303/308 midterm tips 1 point, 1 comment
u/Altruistic-Set1428: “Got both of these midterms one day apart and im a bit worried. Would love any tips/insight on how brutal they are. Just doing study questions/reading powerpoints/making notes but idk, theres so much content....”
Spring 2023
Biol 308 discord? 1 point, 0 comments
u/TurboTwinky28: “is there a 308 server? anyone got a link to it?”
Adviced needed - BIOL 308 vs BIOL 359 5 points, 1 comment
u/Luvvul1234: “We are into week 2 of spring term and I urgently need to add one of these courses, BIOL 308 heard horrible things about it and BIOL 359 I am unsure of what to expect. Any advice is appreciated.”
u/dumbassinwaterloo: “BIOL 359 is not difficult and it is interesting. I personally would pick BIOL 359 over BIOL 308, and I have taken both.”
BIOL 342 vs BIOL 308 vs BIOL 341 ? 2 points, 2 comments
u/Luvvul1234: “Hello guys, If anyone had taken any of the courses mentioned in title, how was your experience? Which one should be the most manageable? Kind of having a hard time trying to find 3rd and 4th year BIOL & CHEM average/easy electives. …”
Biol 308 1 point, 1 comment
u/l_bb0: “I know the prof says the textbook is required but is it really necessary? Can you get by without using it? Always looking to cut out textbooks as much as possible.”
Winter 2023
Biol 308 - Bruce Wolff - What sort of hell am I walking into? 1 point, 2 comments
u/TurboTwinky28: “I initially tried taking 308 back in Fall with Bruce Reed but I dropped it because the man was so dry, his lectures seemed closer to rambling than actual coherent teaching and his slides looked like essays. …”
Genetics 1 point, 3 comments
“TL;DR what courses can I take that are based off genetics and what requirements do I need to become a geneticist? …”
u/StrictOlive: “… Edit: Since biol 309 and 308 and prerequisites for 434 (and are basically entirely transcription and translation content), if you manage to finish those plus 434 and not hate your life in the process, then you'll do just fine pursuing a career as a geneticist”
Fall 2022
I failed BIOL 308 10 points, 4 comments
Failing a 300-level Biology course 10 points, 9 comments
u/Diligent_Composer_94: “Gl tomorrow G. What course?”
u/dumassinwaterloo: “When I took BIOL 308 the prof gave us practice questions”
how to prepare for biol 308 final? 3 points, 2 comments
u/-Leviathan-: “With all due respect (and also please take this with a grain of salt as it's been two years since I took it), BIOL 308 pretty much only builds on the knowledge you should already have about transcription and translation. …”
Check it elsewhere for Fall 2026
- Undergraduate Calendar, 2026–27The official entry
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- Schedule of Classes, Fall 2026Instructors, rooms, live seats
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- Course outlinesSyllabi from past terms (UW login)
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