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BIOL 434Human Molecular Genetics

Units
0.50
Faculty
Science
Subject
Biology

When it runs

  1. F24
  2. W25
  3. S25
  4. F25
  5. W26
  6. S26
  7. F26
  8. W27
  9. S27

Ran in 3 of the last 7 terms. Winter 2027: not on the schedule. Spring 2027: schedule not out yet.

Recent advances in human molecular genetics will be examined with emphasis on how human disease-causing genes are mapped, identified, isolated, and characterized. Examples will draw from research on Duchenne muscular dystrophy, Huntington disease, cystic fibrosis, Alzheimer disease, cancer, vision defects, and other disorders.

Prerequisites

  • Complete all of the following
    • Must have completed the following:
      • BIOL308 - Principles of Molecular Biology (0.50)
    • Complete 1 of the following
      • Must have completed the following:
        • BIOL235 - Foundations of Molecular Biology (0.50)
      • Must have completed the following:

Antirequisites

None listed.

Leads to

No course lists it as a requisite.

Fall 2026 sections

Enrolment from UW Open Data, which can trail Quest by up to two days. Instructors and rooms: Schedule of Classes.
SectionClassEnrolledMeets
LEC 001793439 / 80MWF 09:30–10:20

Reviewed on UW Flow

82% liked it39% easy92% useful

From 17 ratings and 7 comments on UW Flow. The most helpful comments, quoted as written, without names. Read them all on UW Flow.

  • Now that I'm reviewing for the final I actually regret I haven't studied much during the term... This is actually a very interesting course with quite some useful and fascinating content, some of which overlap with BIOL 469/266. If you are interested in genetics, it should be a fun ride. Based on the few lectures I attended, discussions occurring in class could also be intriguing sometimes as many people there genuinely enjoy the subject.
    Midterm and term paper are all very fair. I marked "easy", not easy as in a sense that you could ace it without trying (I failed miserably), but easy as if you did put some effort, nothing there to trick you. Dr. Duncker has been a great prof, clear,…

    Dec 2017 · liked it · 1 found this helpfulOn UW FlowRemove this

  • Bernie Dunker is a great proff, he genuinely enjoys teaching!
    Highly recommend going to class, because he adds lots of notes to his slides. The textbook is also very helpful to review diagram captions.
    Overall great course, very interesting! He plays movies every other Friday, he also gets you to analyze journal articles, which is a super useful skill for a 4th year bio student to have.
    Many students do poorly on the first midterm, but end up with a decent mark after the final project and exam.

    Mar 2015 · liked it · 1 found this helpfulOn UW FlowRemove this

  • Super interesting class and I enjoyed it a lot. The grading was very fair as well

    Apr 2026 · liked itOn UW FlowRemove this

  • This was one of the best courses I’ve taken. The material is genuinely interesting if you’re into human genetics, and it’s taught in a way that makes complex concepts feel clear and manageable. Dr. Duncker does an excellent job breaking down detailed topics without oversimplifying them, and you can tell he’s extremely knowledgeable in the field.
    What really sets this course apart is the structure. Fridays were especially engaging—we either analyzed real research papers, had guest lectures from experts, or watched documentaries that connected course concepts to real-world applications. This made the course feel dynamic and relevant rather than just memorization-heavy.
    Overall, I’d highly…

    Feb 2026 · liked itOn UW FlowRemove this

  • The content is super interesting and Professor Buckley is super knowledgable, but there is sooo much content. You have to be prepared to keep on top of the lectures because it is super easy to fall behind. The grade breakdown was divided into 2 midterms and a final paper, so no exam. The midterms were open book, 2.5 hours long and were all long answer application questions. Professor Buckley does give you tips on how to optimize your notes for quick reference during the tests, but they are still challenging even with your notes next to you so you do still need to study.

    Mar 2023 · liked itOn UW FlowRemove this

Discussed on r/uwaterloo

17 posts and comments in 17 threads mention BIOL 434, August 2012 to December 2024. Quoted word for word, newest first; each reply sits under the post and the comment that started its branch. Search r/uwaterloo for newer posts.

Winter 2023

Genetics 1 point, 3 comments

“TL;DR what courses can I take that are based off genetics and what requirements do I need to become a geneticist? …”

u/StrictOlive: “I took BIOL 434 (human molecular genetics) this past fall. It was taught by a genetics counselor from Grand River and focused on many common genetic diseases and the respective mutations that cause them. …”

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Fall 2021

Spring 2021

Winter 2021

Most useful course you have taken? 1 point, 1 comment

[deleted]: “So far, the most useful courses I've taken are BIOL 309 (molecular biology techniques), BIOL 469 (genomics), BIOL 308 (molecular biology), BIOL 431(bacterial genetics) and BIOL 434 (human genetics). What are your most useful courses?”

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Fall 2020

Biol 434 study group 1 point, 3 comments

[deleted]: “Hey, does anyone want to make a biol 434 study group? I'm also in biol 433, biol 376 and biol 342 if anyone is interested in making in a study group.”

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Fall 2019

Fall 2017

Any way to disable UWCourseLinker from posting? 16 points, 26 comments

“posting a reply to my comment I find the bot annoying.”

u/Jackhofmann: “PSYCH 483 PSYCH 484 PSYCH 485 PSYCH 486 PSYCH 490R PSYCH 499A PSYCH 499B PSYCH 499C PSYCH 621 PSYCH 630 PSYCH 677A PSYCH 704A PSYCH 704B PSYCH 707 PSYCH 710 PSYCH 714 PSYCH 717 PSYCH 720A PSYCH 721A …”

u/Jackhofmann: “… BIOL 342 BIOL 345 BIOL 349 BIOL 350 BIOL 354 BIOL 359 BIOL 370 BIOL 376 BIOL 377 BIOL 416W BIOL 434 BIOL 439 BIOL 443 BIOL 444 BIOL 447 BIOL 448 BIOL 452 BIOL 456 BIOL 462 BIOL 469 BIOL 470 BIOL 472 BIOL 473 BIOL 479 BIOL 483 BIOL 490A BIOL 490B BIOL 492 BIOL 498A BIOL 498B BIOL …”

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Check it elsewhere for Fall 2026

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