73 courses in the 1973–74 Undergraduate Calendar, read from the scanned original. The text comes from OCR, so check the scanned page before relying on a detail.
Notes
Department of Chemistry
Faculty listed in 1973–74
Professor and Chairman of W.A.E. McBryde, M.A. (Toronto), Ph.D, { Virginia), F.CI.C.
Details of the undergraduate programmes offered by theFaculty of Science are to be found on page 236. Prerequisites for a course are a reliable guide to the background necessary Jor the course. In lieu of the specific courses listed, an equivalent background from Waterloo or elsewehere is acceptable. With consent of the instructor, prerequisites may be waived in exceptional cases.
A pre-university or remedial course in chemistry that covers the material considered essential preparation for first-year university courses. The states of matter; their properties and transformations. The nature of heat and its effect on chemical reactions. The rates of chemical reactions. Formulae, nomenclature, stoichiometry. Composition of solutions, solubility. Qualitative and quantitative aspects of chemical equilibrium. Acids and Bases. Oxidation and Reduction. Atomic structure. The chemical bond and the shapes of molecules. The periodic classification. Successful completion of this course fulfills the University Admission requirements where high school Chemistry is necessary. Offered by correspondence only, one term. No university credit.
Stoichiometry, properties of gases, liquids and solutions, gas phase cheniical equilibria, ionic equilibria in aqueous solutions, - oxidation-reduction, chemical kinetics. 3 lectures, 1 tutorial, fall term. (For students registered in the Year I Engineering programme.)
The basic chemistry of the important classes of aliphatic and aromatic 1 compounds. A laboratory course on preparative organic chemistry and organic techniques accompanies the lectures. 3 lectures, 3 hours laboratory, alternate weeks, fall and winter terms
An introduction to the important classes of heterocyclic compounds and natural products. Prerequisite: Chemistry 26* 3 lectures, fall and spring terms
Chemistry 111* continued tp include chemical equilibria and rates of reaction. Prerequisite: Chemistry 111* 3 lectures, 3 hours laboratory alternate weeks, winter term. Laboratory optional for non-science students.
Chemistry 111*-112* are designed for students who have NOT completed Ontario Grade 13 chemistry and who may wish to pursue higher level chemistry courses. Only in exceptional circumstances will this course sequence be open to students who have taken Ontario Grade 13 chemistry or its equivalent. Such students should take 121* followed by 122°. Credit will not be allowed for both 111*-112* and 121*-122*.
Stoichiometry and structure; periodic’atomic properties and their chemical implications; descriptive chemistry of selected compounds; - special interest topics. Prerequisite: Grade 13 Chemistry, Mathematics (Functions and Relations; and Calculus) 3 lectures, 3 hours laboratory, fall term. Laboratory optional for. non-science students
Ionic equilibria in aqueous solutions; oxidation-reduction; reaction kinetics and mechanisms in aqueous solutions; special interest topics. Prerequisite: Chemistry 121* 3 lectures, 3 hours laboratory, winter and spring terms. Laboratory optional for non-Science students
Equilibrium, energetics and mechanisms of reactions. Prerequisite: Chemistry 121*. 3 lectures, 3 hours laboratory, winter term only. Laboratory optional for non-Science students
CHEM 210Non-Aqueous Solvents and Non-Transition Metal Chemistry »
Modern acid-base theory. Behaviour in specific non-aqueous systems. Application to the synthesis and reactivity of non-transition metal compounds. (Primarily for Honours Chemistry, Honours Applied Chemistry and Honours Biology and Chemistry.) Prerequisite: Chemistry 121*-122* 2 lectures, 3 hours laboratory, fall term only. The laboratory is optional for all students except those enrolled in Honours Chemistry, Honours Chemistry (Physics or Mathematics Option) and Honours Applied Chemistry.
| Concepts of molecular orbital and valence bond theories. o, 7 and § bonding’in compiex polyatomic inorganic molecules. Relationship of bonding to stereochemistry and electronic structure in specific groups of compounds. (Primarily for Honours Chemistry, Honours Applied Chemistry and Honours Biology and Chemistry.) Prerequisite: Chemistry 121* 2 lectures, offered in winter and spring terms.
CHEM 218Development of Chemical Bonding and Structure
Current models of bonding in Inorganic Chemistry. Prediction of stereochemistry and electronic structure. Inorganic nomenclature. Prerequisite: Chemistry 121* 2 lectures, I tutorial, fall term.
Group trends in main group chemistry. Emphasis will be placed on correlation of structure with physical properties in various groups of compounds. Prerequisites: Chemistry 218* 2 lectures, I tutorial, winter term.
Department of Chemistry
The principles underlying quantitative chemical measurements, with experiments to develop confidence in personal laboratory techniques and to provide experience in comparing and choosing analytical methods. (Primarily for Honours’ Chemistry, Honours Applied Chemistry and Honours Biology and Chemistry.) Prerequisite: Chemistry 121* and 122* J lecture, 6 hours laboratory, offered in fall and winter terms.
CHEM 221Analytical Chemistry. of Multi-Component Systems
Applications of electroanalytical methods, spectroscopic methods, and analytical separations to the quantitative description of multi-component systems. (Primarily for Honours Chemistry, Honours Applied Chemistry and Honours Biology and Chemistry.) Prerequisite: Chemistry 220* 2 lectures offered in fall,. winter and spring terms.
An introductory survey of the principles and applications of spectroscopic techniques used in the modern chemical laboratory. Topics will include electronic, vibrational and rotational spectroscopy, and magnetic resonance spectroscopy. 2 lectures per week, 2 terms. (full-year course).
A variety of classical and modern methods will be discussed in principle, and applied in the laboratory. Prerequisite: Chemistry 121* and 122* » 2 lectures, 6 hours laboratory, fall term only.
CHEM 227Chemical Analysis 2 - 231 Chemical Bonding and Structure 240° Introductory Theoretical Chemistry
The evolution of some modern analytical methods will be discussed in the lectures. The laboratory will deal with their application to contemporary pfoblems in chemistry and other sciences. Prerequisite: Chemistry 226* or 220%. 2 lectures, 6 hours laboratory, winter term only.
Classical and wave theories of the electronic structure of atoms. The Periodic Table. Formation and properties of ionic covalent and coordinate bonds. Bonding in molecular ionic and metallic solids. Molecular orbital and valence bond theories. Some methods for the establishment of molecular shapes. Application of the concepts: of chemical bonding to the stereochemistry, structure and properties of main group element compounds. Relationship of bonding to reactivity and electronic structure. Periodicity and periodic trends in group chemistry. Synthesis of selected groups of inorganic compounds. Prerequisite: A first year Chemistry course, e.g. Chemistry 121*-122* 2 lectures, for two terms (full-year course).
Partial differentiation and the calculus of several variables; solution of ordinary differential equations with emphasis on the special functions occurring in chemistry (e.g. Hermite, Legendre and associated Laguerre functions); fundamentals of linear algebra including vector spaces and matrices; introduction to operator concepts. All of these mathematical methods will be illustrated with examples taken from modern chemistry and their employment in further chemistry courses will be discussed. Prerequisites: Chemistry 121* and Mathematics 130 2 lectures, 1 tutorial, offered in fall and winter terms.
250° Introductory Thermodynamics
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Laws 0,1,2,3 of Thermodynamics and their application to the properties of ideal systems; thermochemistry; spontaneity of chemical reactions and the criteria for chemical equilibrium; derivation of the phase rule and its application. Prerequisites: Chemistry 121* and 122*; Mathematics 130 2 lectures, 1 tutorial, offered in fall and winter terms.
CHEM 251Application of Chemical Thermodynamics to Real Systems
Partial molal quantities; Gibbs chemical potential and non-ideal systems; chemical equilibrium; theory of electrolytes. Prerequisites: Chemistry 250* - 2 lectures, 1 tutorial, offered in fall, winter and spring terms.
A review of classical wave motion; the postulates of quantum mechanics; quantum mechanics of the hydrogen atom; angular momentum and simple coupling schemes; selection rules and atomic spectroscopy of hydrogen-like systems and the helium atom; discussion of multi-electron atoms; fine and hyperfine structure. Prerequisite: Chemistry 240* 2 lectures, 1 tutorial, offered in fall, winter and spring.
The preparation and reactions of typical organic functional groups examined from the basis of the reaction mechanisms is presented. Spectroscopic correlations of these functional groups is introduced. Stereochemistry of organic molecules is discussed. (Primarily for Honours Chemistry, Honours Applied Chemistry and Honours Biology and Chemistry.) : Prerequisite: Chemistry 12]*-122* 2 lectures, 1 tutorial, 3 hours laboratory, offered in fall and winter terms.
The treatment of organic chemistry in Chemistry 261* is continued and extended to aromatic compounds. (Primarily for Honours Chemistry, Honours Applied Chemistry and Honours Biology and Chemistry.) Prerequisite: Chemistry 260* 2 lectures, 1 tutorial, offered in fall, winter and spring terms.
The properties, preparation, reactions and basic structural theory of the common classes of aliphatic compounds. Introduction to electrophilic and nucleophilic reaction mechanisms, Prerequisite: Chemistry 121* and 122* 2 lectures, 1 tutorial, fall term.
The properties, preparation, reactions and basic structural theory of the common classes of aromatic compounds. A continuation of organic reaction mechanisms. Introduction to the chemistry of carbohydrates, proteins, steroids, etc. Prerequisite: Chemistry 266* 2 lectures, 3 hours laboratory, winter term.
(For students needing a full year of Organic Chemistry as a prerequisite to medicine, the sequence 266*-267* should be selected.)
Selected experiments to accompany the lecture work of Year 2 Honours Chemistry (incl. Math and Physics options) and Honours Biology and ’ Chemistry and term 2B Honours Applied Chemistry. Only open to such Students, . 9 hours laboratory, offered in fall winter and spring terms.
Most 300-level honours courses are listed as 2 hours lectures; an additional 1 hour tutorial may be scheduled at the discretion of the instructor.
CHEM 310Transition Metal and Coordination Chemistry
Electronic structure and stereochemistry of complex ions. Metal-ligand bonding. Crystal-field, ligand-field and molecular orbital theories. The spectrochemical series and the trans effect. Magnetochemistry, U.V./visible spectra of transition metal complexes. Prerequisites: Chemistry 210*, 211* 2 lectures; offered in fall and spring terms
An introduction to nuclear stability rules, radioactive decay processes and nuclear structure. a, 8, y, emission. Nuclear reactions, fission; production of heavy elements. Interaction of radiation with matter. Radioisotopes. Brief introduction to actinide chemistry. Prerequisite: Chemistry 121* or equivalent 2 lectures, offered in winter term
CHEM 316An Introduction to Transition Metal Chemistry
The transition elements and their compounds. An elementary approach to crystal and ligand field theory will be used to rationalise the spectra, magnetism, structures and properties of transition metal complex compounds... Prerequisite: Chemistry 218*, 219* or 211* 2 lectures, 3 hours laboratory, fall term.
Ionic and molecular crystals. Close packing and three dimensional lattices. Structures and properties of the metallic elements. Defects in the solid state. Non stoichiometry. Prerequisites: Chemistry 218*, 219* or 211* 2 lectures, winter ferm.
The principles of operation, practical limitations and preferred uses of various devices commonly used to make accurate measurements of importance in modern chemistry. Transducers for temperature, pressure, solution potential, optical absorptivity, etc. Prerequisites: Chemistry 220* or 226*-227* 2 lectures, 3 hours laboratory, offered in winter term
An introduction to the chemistry of amino acids, peptides, proteins, 1 nucleic acids, carbohydrates and lipids. Prerequisites: Chemistry 261* or 267* 2 lectures; offered in fall. winter and spring terms.
A 3 hour laboratory will be given for Honours Biology and for General Science students.
CHEM 337Biochemistry Carbohydrates, lipids, proteins, hormones, nucleicacids, and vitamins.
Metabolism of these groups of compounds. Physicochemical aspects of biochemistry.
Prerequisite: Chemistry 260*, 261* or 266%, 267* or equivalent 2 lectures, two terms (full-year course for correspondence students, equivalent to 332*-333*)
CHEM 344Inorganic and Nuclear Survey of transition metal chemistry including ligand field theory of
Chemistry coordination compounds and an introduction to organometallic chemistry. Introduction to nuclear and radiochemistry. Prerequisites: a background in Chemical Bonding, e.g. Chemistry 211* or 218* or 231 2 lectures, for two terms (full-year course)
CHEM 351Statistical Thermodynamics Ensembles, postulates of statistical mechanics; Boltzmann, Fermi-Dirac,
and Bose-Einstein Statistics; microcanonical, canonical and grand canonical ensembles; Equilibrium statistical mechanics and statistical thermodynamics; application to ideal gases.
Prerequisites: Chemistry 240*, 250* 2 lectures; fall and spring terms
CHEM 353Introduction to Polymer Basic definitions and polymer nomenclature, molecular weight averages
Science and distributions, polymer constitution, configuration and conformation, ,Step-growth and free-radical chain-growth polymerization and copolymerization. Prerequisites: Chemistry 250* and 260* or equivalent 2 lectures; fall and spring terms
CHEM 354Applied Kinetics Introduction to kinetics and mechanism of elementary chemical
processes in homogeneous systems, reversible, consecutive and simultaneous reactions, interpretation of kinetic data. Application to industrial processes, both batch and continuous.
Prerequisite: Chemistry 250* or 356* 2 lectures; winter term \
An introductory survey of the thermodynamics of ideal systems; the application of thermodynamic principles to the study of solutions, phase equilibria, chemical equilibrium and the properties of electrolytes: Prerequisites: Chemistry 122* and Math 130 2 lectures, 3 hours laboratory; fall term
An introductory survey of the concepts and principles of quantum mechanics; the application of these principles to the study of atomic and molecular structure and spectra, and to photochemical phenomena. Chemical kinetics. Prerequisites: Chemistry 356* 2 lectures, 3 hours laboratory; winter term
Acidity and basicity of organic compounds. Formation and ‘reactions of enolate anions with emphasis on their synthetic utility. Cycloaddition reactions. Prerequisite: Chemistry 360* or 261* 2 lectures; winter term
A 3 hour laboratory will be given for Honours Biology and Chemistry students.
A number of topics in physical and organic chemistry treated from a semi-empirical consideration of molecular structure (e.g. MO theory and reactivity). Prerequisites: Chemistry 240*, 261* 2 lectures; winter term.
The organic chemistry involved in selected industrial processes will be discussed. Petroleum chemistry, synthesis of dyestuffs, pharmaceuticals, pesticides, organic polymers, etc. Prerequisite: Chemistry 261* 2 lectures; fall and spring terms
CHEM 366Structural and Synthetic Organic Chemistry
Stereochgmistry of organic molecules; synthesis of selected organic compounds examined in detail with emphasis on cyclo-addition reactions ; and condensation reactions. Prerequisites: Chemistry 261* or 267* 2 lectures, 3 hours laboratory; fall term
Some of the following topics will be discussed: photochemistry, organometallic compounds, organic compounds of commercial interest, natural products. Prerequisites: Chemistry 360* or 366* 2 lectures, winter term
Selected experiments to accompany lecture work of year 3 Honours and Applied Chemistry. ~ Prerequisite: Chemistry 291* . _9 hours laboratory; fall and spring terms
The development of chemistry will be traced from alchemy to the 20th century. The contributions of famous scientists to the concepts and models of modern chemistry will be emphasized. 2 lectures; winter term
Ideal crystals, factors affecting the stoichiometry of inorganic crystals. Common lattices adopted by ionic compounds. Non-ideality, lattice defects, order-disorder. Non-stoichiometric compounds. Methods of structure determination including X-Ray and Neutron diffraction. Metals, semi-conductors and insulators. Prerequisite: Chemistry 211* or 218* 2 lectures, fall term
The synthesis, characterization and reactivity of compound containing metal-carbon covalent bonds. Metal carbonyls and their derivatives. Olefin, acetylene, 7-arene and related complexes. The nature of the metal-carbon bond. Catalysis by transition metal organometallics. Prerequisite: Chemistry 310* or equivalent 2 lectures, fall term
Mechanisms of substitution reactions in solution. Hydrolysis, aquation, anation, fast reactions of transition metal complexes. Octahedral, square planar and tetrahedral systems will be treated in detail. Experimental techniques. Prerequisite: Chemistry 310* 2 lectures, winter term
The chemistry of inorganic compounds and processes of industrial importance will be discussed.. Inorganic polymers; catalysis by inorganic systems including nitrogen fixation, hydrogenation, hydroformylation. Synthesis and purification of metals. Prerequisites: Chemistry 210*, 211* 2 lectures, fall term
CHEM 417Synthesis and Structure of Inorganic Compounds
The chemistry of selected groups of important inorganic compounds will be discussed to emphasize synthetic methods, structure and reactivity. Prerequisite: Chemistry 310*.
2 lectures, winter term
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. _ 419* Biological Aspects of Survey of metal binding groups in.enzymes, proteins, amino acids and
_. Inorganic Chemistry
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other molecules of biological importance. Role of metals in biological processes. Oxygen transport, electron transfer, enzyme catalysis, nitrogen fixation. Specific groups of important metal complexes to be discussed will include: heme proteins, ferredoxins, vitamin B,, coenzymes, carboxypeptidase, xanthine-oxidase, etc. Poisoning and blocking of active sites by complexation; mercury pollution. Design and use of model systems. Prerequisite: Chemistry 310* or 316* 2 lectures, winter term
Selected topics in modern analysis of inorganic materials such as rocks, ores, ceramics, metals and alloys. Atomic flame spectroscopic methods, analytical X-ray techniques, methods for ultra-pure materials, trace and
_ micro determinations.
Prerequisite: Chemistry 221* 2 lectures, fall term
The techniques and fundamental principles of infrared, mass spectrometry and NMR as applied to the qualitative identification of chemical compounds. Prerequisite: Chemistry 221* 2 lectures, winter term
Practical and theoretical topics required for understanding, selecting and applying basic methods of quantitative analysis. Primarily for students in upper years of Honours Biology. Prerequisite: a first year chemistry course 2 lectures, 3 hours laboratory, fall term
CHEM 428Chemical Measurements for Biologists 2 ' 432* Biochemistry 3
Extension and refinement of measuring techniques by proper choice and use of instruments, emphasizing topics related to modern biological studies. Primarily for students in upper years of Honours Biology. Prerequisite: Chemistry 427* or consent of instructor 2 lectures, 3 hours laboratory, winter term
Kinetics, stereospecificity, structure and function of enzymes, bio-energetics, oxidative phosphorylation. Prerequisite: Chemistry 333* 2 lectures, fall term
Chemistry and biosynthesis of porphyrins. Metabolism of amino acids, purines and pyrimidines. Role of vitamins in biological transformations. Respiration, muscular contraction. Prerequisite: Chemistry 432* 2 lectures, winter term
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_ 434° Applied Biochemistry
Department of Chemistry
Chemistry and function of antibiotics; blood coagulation and related topics. Immuno-chemistry. Nutritional aspects of food. . Prerequisite: Chemistry 333*.- -2 lectures, winter term
Selected topics and techniques in modern biochemistry; energy transfer, transport across membranes, comparative aspects of metabolism, mechanism and kinetics of enzyme activity, structural macromolecules. Prerequisite: Chemistry 337. 2 lectures (Full-year course for correspondence students, equivalent to 432*-433*)
Basic group theory, irreducible representations, molecular symmetry groups, character tables, reduction of representations. These various concepts will be illustrated by application to specific examples. Prerequisite: Chemistry 252* 2 lectures, fall term
Applications of statistical mechanics to systems of interacting molecules: imperfect gases, liquids, solids, surfaces, and solutions. Prerequisite: Chemistry 351* 2 lectures, fall term
Selected topics in quantum chemistry. Such topics may include: fundamental problems in quantum chemistry, physical nature of the chemical bond, stationary and nonstationary state problems, applications of quantum mechanics to systems of chemical interest. Prerequisite: Chemistry 252* 2 lectures, winter term
An introduction to the physical chemistry of surfaces. Qualitative and quantitative descriptions of surfaces and interfaces and the development of relevant techniques and theories. Application to surface tension, spreading, wetting, adsortpion, and other interfacial phenomena. Prerequisites: Chemistry 250*, 251* 2 lectures, fall term
Electrolytic conductance and transport, thermodynamics of electrolytic cells. Reversible and irreversible electrode processes, metallic corrosion; study of selected industrial electrochemical processes. Prerequisites: Chemistry 250°, 251* 2 lectures, fall term
An introduction to heterogeneous catalysis. Examination of the physical manifestations of catalysis and the development of experimental techniques and theoretical methods for the measurement and elucidation of catalytic phenomena. Prerequisite: Chemistry 454* 2 lectures, winter term
Selected experiments to describe properties of polymers and polymerization processes. Prerequisite: Chemistry 353* or equivalent 1 lecture, 3 hours laboratory, winter term
Elucidation and identification of organic structures by contemporary spectroscopic techniques Prerequisites: Chemistry 260*, 350* 2 lectures, fall term
One haif of the semester will be devoted to principles of organic synthesis. For the second half of the semester students can opt for one of the following topics (a) Molecular rearrangements (b) Photochemistry (c) Organometallics (d) Heterocyclic compounds. Prerequisite: Chemistry 361* 2 lectures, winter term