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CHEM 266Basic Organic Chemistry 1

Units
0.50
Faculty
Science
Subject
Chemistry

When it runs

  1. F24
  2. W25
  3. S25
  4. F25
  5. W26
  6. S26
  7. F26
  8. W27
  9. S27

Ran in 7 of the last 7 terms. Winter 2027: scheduled, 1 lecture section. Spring 2027: schedule not out yet.

Structure, nomenclature, and reactions of important classes of organic compounds. Stereochemistry and its role in reaction mechanisms.

Prerequisites

  • Must have completed at least 1 of the following:
    • CHEM123 - General Chemistry 2 (0.50)
    • CHEM125 - Chemical Reactions, Equilibria and Kinetics (0.50)

Antirequisites

  • Not completed nor concurrently enrolled in any of the following:
    • CHEM262 - Organic Chemistry for Engineering (0.50)
    • CHEM264 - Organic Chemistry 1 (0.50)
    • NE222 - Organic Chemistry for Nanotechnology Engineers (0.50)

Leads to

Fall 2026 sections

Enrolment from UW Open Data, which can trail Quest by up to two days. Instructors and rooms: Schedule of Classes.
SectionClassEnrolledMeets
LEC 0016989378 / 380TTh 10:00–11:20
LEC 0026990352 / 380MWF 09:30–10:20
TST 1017147730 / 760Oct 26 17:30–18:50
Nov 23 17:30–18:50

Winter 2027 sections

Enrolment from UW Open Data, which can trail Quest by up to two days. Instructors and rooms: Schedule of Classes.
SectionClassEnrolledMeets
LEC 00169110 / 60Online or by arrangement

Reviewed on UW Flow

53% liked it23% easy81% useful

From 311 ratings and 90 comments on UW Flow. The most helpful comments, quoted as written, without names. Read them all on UW Flow.

  • Honestly, this course isn't as bad as everyone makes it out to be. Yes, the content can be difficult, but if you go to class and do the practice that is recommended, it is possible to do well. I would recommend buying the textbook in order to do the TopHat quizzes (bonus 5%) and completing the Kritiks (bonus 10%). The profs clearly care about the students, and want you to do well. The tests are fair, and they provide tests from previous years, along with the answers, in order to practice. Plus, you are allowed a double-sided cheat sheet for the tests and the final exam. I ended up doing better in this class than chem 120, and chem 123. The content was interesting, and leads into a lot of…

    Jan 2023 · liked it · 3 found this helpfulOn UW FlowRemove this

  • I am writing as someone who achieved 100% on this course (got a 100% on the exam and it was my final grade). First of all, I am not doing this to show-off at all or make myself seem better than anyone. I am only writing this to give people hope that they can do well if they use the correct strategies. I simply want to pass my wisdom/experience (I guess haha? not to say im wiser than anyone LMAO) to the next generation of young organic chemists. DO NOT LISTEN TO PEOPLE WHO SAY THIS IS HARD OR THAT NO MATTER HOW HARD YOU TRY YOU WILL DO BAD. I had no hopes for this course because so many people dropped my confidence saying this is a hard course BUT DON'T LISTEN TO THEM. Many people say it is…

    Dec 2023 · liked it · 2 found this helpfulOn UW FlowRemove this

  • If I had a dime for every tear shed for this course, I would own Tesla. I think the combo of being really bad at chem and taking it online really took me out. I BARELY passed. Still passed tho :)

    Jun 2021 · didn’t like it · 2 found this helpfulOn UW FlowRemove this

  • This course is like a haunted house.
    Organic chemistry was easily the hardest class I’ve ever taken, and it humbled me fast. Taking it alongside a full course load (including three labs) made it even more challenging. This is a course that truly requires constant practice and review, which is just not really realistic for science students who have multiple other science courses and labs that also require a lot of time and effort.
    The beginning of the course feels manageable, but once the content ramps up (after midterm 1), it really ramps up. By the time you reach the exam, you’re expected to know around 30 reactions, all of their reagents, mechanisms, pathways, exceptions, and special…

    Dec 2025 · didn’t like it · 1 found this helpfulOn UW FlowRemove this

  • This course gets a lot of hate, however I think the content is fairly straightforward if you keep up with it during the term. When the content is tested together, it is very overwhelming and that is why it is important to keep with the course. I personally found this course easier than CHEM 123. My best advice is to try to get 100s on the Kritiks, and prelec quizzes, and try to enter the exam with a higher mark because the exam is very content heavy.

    Jan 2024 · liked it · 1 found this helpfulOn UW FlowRemove this

Discussed on r/uwaterloo

400 posts and comments in 306 threads mention CHEM 266, December 2011 to December 2024. Quoted word for word, newest first; each reply sits under the post and the comment that started its branch. Search r/uwaterloo for newer posts.

Fall 2024

BOOMSHAKALAKA YES GOODDDDD!!!! 63 points, 9 comments

“i passed orgo guys, christmas miracle i can sleep in peace. goodnight and goodluck to everyone i hope everyone passes all their courses and it will get better i love you all <3”

u/Strategos_Kanadikos: “I remember cramming a night for this, I was so happy to come out with 72% even though that was the lowest mark on my transcript. This CHEM266? That course was no joke...”

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Chem120 Midterm 1 point, 7 comments

“So i failed both of the midterms which were weighted 20% each. Do you know any one that happens to be an upper year who failed 2 midterms but miraculously passed the course? …”

u/voxaun: “i passed but i got 53. retook the course and got 85”

u/voxaun: “tbh i would WD if i were you T\T it's better to retake it & know the concepts so you can succeed in chem 123 and chem 266. i failed one midterm & i did poorly on the exam”

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Spring 2024

chem 266 1 point, 5 comments

u/voxaun: “i'm super anxious about chem 266 this fall, and i want to prepare for it during the remainder of august. i nearly failed chem 120, but i did much better in chem 123. what are important concepts to review for chem 266? i've taken a look at the course outline but i'm unsure.”

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Check it elsewhere for Fall 2026

Calendar versions

Undergraduate Calendar