uwloo

BIOL 365Methods in Bioinformatics

Units
0.50
Faculty
Science
Subject
Biology

When it runs

  1. F24
  2. W25
  3. S25
  4. F25
  5. W26
  6. S26
  7. F26
  8. W27
  9. S27

Ran in 2 of the last 7 terms. Winter 2027: scheduled, 2 lecture sections. Spring 2027: schedule not out yet.

This course covers bioinformatics methods with an emphasis on analysis of high-throughput "-omics" data. Topics include analysis of genome-scale gene and protein expression, construction of species and gene trees from molecular sequence data, and analysis of biological systems using bioinformatics tools. Practical experience with bioinformatics tools and datasets will be provided through computational laboratory exercises.

Prerequisites

  • Complete all of the following
    • Must have completed the following:
    • Must have completed at least 1 of the following:
      • BIOL266 - Introduction to Computational Biology (0.50)
      • CHEM140 - Introduction to Scientific Calculations (0.50)
      • CS116 - Introduction to Computer Science 2 (0.50)
      • CS136 - Elementary Algorithm Design and Data Abstraction (0.50)

Antirequisites

None listed.

Leads to

Winter 2027 sections

Enrolment from UW Open Data, which can trail Quest by up to two days. Instructors and rooms: Schedule of Classes.
SectionClassEnrolledMeets
LEC 00167630 / 100M 14:30–16:20
LEC 701253751 / 9999Online or by arrangement
LAB 10167640 / 50W 14:30–16:20
LAB 10268730 / 50W 08:30–10:20

Reviewed on UW Flow

68% liked it54% easy77% useful

From 25 ratings and 7 comments on UW Flow. The most helpful comments, quoted as written, without names. Read them all on UW Flow.

  • Poorly structured course. The lectures were confusing and the slides were not helpful when studying. Dr. McConkey is a very smart guy who clearly has lots of experience in bioinformatics, but his experience doesn't translate very well to teaching. He spent lots of time on things we weren't tested on, but glossed over things that were worth 15 marks on the final. Final was absolutely brutal.
    That being said, the course content I did manage to get into my head during this course (mostly thanks to studying in a group) was very relevant and applicable when I did a co-op job in bioinformatics.

    Jul 2019 · didn’t like it · 1 found this helpfulOn UW FlowRemove this

  • AVOID THIS COURSE. The prof is SUPER lazy. He barely gets assignments out on time, let alone get them back to you marked. Will mumble through each lecture and will himself not understand what he wants you to know. The content would be useful if he taught it effectively. The main reason why I took this course is because I wanted to learn how to use R to analyze data. Unfortunately, he gives you the R script for the assignments, so you do not get to learn that. Also, the final is 5 20 mark long answer questions. Saying this as he did not say this in class. Many people were very blind sided.

    May 2019 · didn’t like it · 1 found this helpfulOn UW FlowRemove this

  • This course won me over. As a biochem student, I'm not naturally engaged by computational science - I took it because I wanted to improve my computer literacy, and since bioinformatics are a good skillset for any scientist to have.
    Buuut I actually loved the course. It's surprisingly useful and relevant to my other courses and coops, and it's great to have a formal introduction to a whole plethora of databases/analysis websites. I was worried to find out that the rest of the class is in computational biology, but any programming that you do for the course has tutorials along with it, so it's not a big deal if you have zero experience like me.
    I found the first unit or two a bit dry…

    Mar 2017 · liked it · 1 found this helpfulOn UW FlowRemove this

  • This course is relatively light. The assignments are too few and too infrequent to really be a major source of learning or assessment. It's fairly reasonable to get 100% on all of the assignments. The major issue were the exams, which most people were unprepared for but were incredibly reasonable. This was very memorization heavy, and would benefit from a more challenging set of assessments and a greater focus on the applications and not just memorization.

    May 2026 · liked itOn UW FlowRemove this

  • An interesting course that touched upon different bioinformatics topics. The lab component focused on the use of R and its applications in gene finding and phylogenetic analysis. There was also a lot of time put into understanding the NCBI both in the lectures and in the lab. Some of the lecture topics included databases, sequence alignments, BLAST, phylogeny, and gene expression. The midterm for this offering of the course was an online LEARN quiz, that consisted of 10 multiple-choice questions and the rest were short answer questions. However, the final exam was in-person and covered all the material taught in the course.

    May 2024 · liked itOn UW FlowRemove this

Discussed on r/uwaterloo

35 posts and comments in 34 threads mention BIOL 365, August 2012 to December 2024. Quoted word for word, newest first; each reply sits under the post and the comment that started its branch. Search r/uwaterloo for newer posts.

Fall 2024

I am looking to get a high average my 3rd and 4th year in Honor Science any course tips? 9 points, 7 comments

“I currently have completed all my pre-requisite courses for the postgraduate program I want to apply for. The only thing I am missing is the high average for my best 2 years of undergrad. …”

u/mustard_tiger6: “The easiest science courses in my experience are BIOL 433 with Lemieux, BIOL 449, BIOL 359 for biology. If you can code a bit, BIOL 469 and BIOL 365 are reasonable too. I would use uw flow and look at chem, kinesiology, health, psychology, sociology, anthropology courses.”

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Winter 2024

Winter 2023

Spring 2022

BIOL 266 or BIOL 365 2 points, 2 comments

u/hoemaster123: “I am trying to plan out my courses for next year and I want to take a bioinformatics course, but can only fit one in for the year. For those that have taken both courses which one would you recommend?”

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Winter 2022

Spring 2021

BIOL 473 vs BIOL 469 vs BIOL 354 1 point, 3 comments

“I have been trying to decide which two out of the above I should take in fall 2021, I need 90s. Any comments about the courses are appreciated, please also let me know when you took the class thank …”

u/BornParsley: “… if you’re decent with bioinformatics/biol266/biol365 you could get 80+. A good portion of your final grade comes from a group research project. If you get a bad group and a bad grade on the research project it will definitely affect your grade. …”

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thinking about what to do with my biology degree (again) 1 point, 7 comments

“I'm in Honours science since im pretty indecisive but im doing courses of a biology student. so far in my biology career i have developed a passionate hatred for molecular biology and chemistry and …”

u/ginavalentinaa: “… but be warned that, while BIOL 266/365 do introduce fundamental concepts, they are not necessarily a good indicator of what the actual work is like. if you find it interesting though and want to explore further, definitely learn coding. …”

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Winter 2021

BIOL 365 3 points, 0 comments

u/blopp199: “Hey, if you are interested in being in a group chat with me for Biol 365, please message me! I don't know anyone in that class so it would be nice to have someone I know :)”

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Check it elsewhere for Fall 2026

Calendar versions

Undergraduate Calendar